{"id":597129,"date":"2026-03-13T08:24:14","date_gmt":"2026-03-13T14:24:14","guid":{"rendered":"https:\/\/cerebrodigital.net\/?p=597129"},"modified":"2026-03-13T09:02:02","modified_gmt":"2026-03-13T15:02:02","slug":"scientists-successfully-create-functional-eggs-from-human-skin-cells","status":"publish","type":"post","link":"https:\/\/cerebrodigital.net\/en\/scientists-successfully-create-functional-eggs-from-human-skin-cells\/","title":{"rendered":"Scientists Successfully Create Functional Eggs from Human Skin Cells"},"content":{"rendered":"\n

Researchers at Oregon Health & Science University<\/strong> developed an experimental technique that converts human skin cells into eggs capable of forming early embryos. This advance represents a potential alternative for treating infertility and opens new reproductive possibilities, though scientists warn it still requires many years of research.<\/p>\n\n\n\n

Scientific Breakthrough That Could Transform Infertility Treatment<\/h2>\n\n\n\n
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A team from Oregon Health & Science University (OHSU)<\/strong> demonstrated an innovative proof of concept that could change infertility treatment. The study, published in the journal Nature Communications<\/strong>, describes a method to convert human skin cells into functional eggs that can generate early-stage embryos.<\/p>\n\n\n\n

The research offers a possible path for in vitro gametogenesis (IVG)<\/strong>, a process to create gametes\u2014eggs or sperm\u2014in the laboratory<\/a>. This technology could benefit millions facing fertility issues, especially women of advanced maternal age or patients who lost viable egg production after medical treatments like chemotherapy.<\/p>\n\n\n\n

Dr. Paula Amato<\/strong>, professor of obstetrics and gynecology at OHSU School of Medicine, states the discovery could have major implications for various family types. Beyond solving infertility, it might enable same-sex couples to have children with genetic material from both partners.<\/p>\n\n\n\n

Despite the excitement, researchers caution it’s in a very early phase. Experts estimate at least a decade more research before determining if it’s safe and effective for clinical trials. The scientific community views it as a key step toward new assisted reproduction methods for those seeking genetically related children.<\/p>\n\n\n\n

How the Technique Converts Skin Cells into Eggs Works<\/h2>\n\n\n\n
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Female embryologist demonstrates freezing straws with embryos and sperm in real IVF laboratory. Work processes and embryo preservation.<\/figcaption><\/figure>\n\n\n\n

The OHSU team’s method introduces “mitomeiosis,” blending mitosis and meiosis cell division processes. Lead researcher Shoukhrat Mitalipov<\/strong>, director of OHSU’s Center for Embryonic Cell and Gene Therapy, says they created a third cell division type once thought impossible.<\/p>\n\n\n\n

Normally, mitosis produces identical cells for tissue growth, while meiosis in reproductive cells halves chromosomes for proper fertilization.<\/p>\n\n\n\n

The experimental technique uses somatic cell nuclear transfer. Scientists extract a skin cell’s nucleus and insert it into a donated egg with its nucleus removed.<\/p>\n\n\n\n

Inside the egg, the environment prompts the skin nucleus to discard half its chromosomes, mimicking meiosis for a 23-chromosome egg. It’s then fertilized via IVF with sperm, creating embryos with both parents’ genetics.<\/p>\n\n\n\n

Researchers produced 82 functional eggs, but most embryos stalled early due to chromosomal issues. Only 9% reached the blastocyst stage, vital for early development.<\/p>\n\n\n\n

The study marks progress in human fertility and assisted reproduction research. Though not yet clinical, it shows promise for lab gamete creation and expanded conception options.<\/em><\/strong><\/p>\n\n\n\n

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