{"id":596656,"date":"2025-06-09T21:21:45","date_gmt":"2025-06-10T03:21:45","guid":{"rendered":"https:\/\/cerebrodigital.net\/?p=596656"},"modified":"2026-03-02T14:56:30","modified_gmt":"2026-03-02T20:56:30","slug":"a-new-biological-key-to-autism-a-japanese-study-suggests-a-possible-prenatal-cause","status":"publish","type":"post","link":"https:\/\/cerebrodigital.net\/en\/a-new-biological-key-to-autism-a-japanese-study-suggests-a-possible-prenatal-cause\/","title":{"rendered":"A new biological key to autism: A Japanese study suggests a possible prenatal cause"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A recent study by researchers at Fukui University in Japan has identified a possible link between certain fatty acids in umbilical cord blood and the development of autism spectrum disorder (ASD). This finding could mark a decisive advance in early diagnosis, understanding its biological causes, and potentially preventive measures during pregnancy.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23-1024x576.png\" alt=\"-\" class=\"wp-image-584482\" title=\"\" srcset=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23-1024x576.png 1024w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23-300x169.png 300w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23-768x432.png 768w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23-1200x675.png 1200w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-23.png 1280w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">A Promising Finding: Umbilical Cord and Autism Connection<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The study found a significant association between levels of dihydroxylated fatty acids (diHETrE) in umbilical cord blood and later autism symptoms. Published in Psychiatry and Clinical Neurosciences, it analyzed blood samples from 200 newborns, who were later evaluated at age six for ASD symptoms and adaptive functioning.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Results showed elevated levels of one metabolite, 11,12-diHETrE, linked to greater social interaction difficulties, while low levels of 8,9-diHETrE related to repetitive or restrictive behaviors. Remarkably, this link was stronger in girls than boys, potentially opening a new gender-focused research line.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Professor Hideo Matsuzaki, the study leader, explained that these compounds have inflammatory properties, and an imbalance during pregnancy could disrupt fetal neurological development. This bolsters the idea that certain prenatal factors significantly influence autism risk.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" width=\"600\" height=\"670\" src=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/Research_news_20240726-e1721962955868.jpeg\" alt=\"-\" class=\"wp-image-584479\" title=\"\" srcset=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/Research_news_20240726-e1721962955868.jpeg 600w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/Research_news_20240726-e1721962955868-269x300.jpeg 269w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Can Autism Be Predicted or Prevented from Birth?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The study also suggests an innovative path: intervening during pregnancy. If future research confirms these results, it might be possible to reduce autism risk by regulating these metabolites through diet, medications, or other methods during gestation. However, the researchers caution that this is just a possibility requiring much more investigation before preventive treatments are proposed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For now, this discovery better elucidates autism&#8217;s complex biological origins and provides a valuable tool for early diagnosis. It also boosts the search for reliable biological markers to offer personalized support from the earliest days of life.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"science-lighting-the-way\">Science Lighting the Way<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Though not definitive, this finding represents real hope for thousands of families. Understanding that autism may have a partially detectable origin at birth brings us closer to faster diagnoses, more effective supports, and perhaps prevention in the future. Science doesn&#8217;t have all the answers yet, but studies like this bring us nearer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Reference:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study). <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pcn.13710\" data-type=\"link\" data-id=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pcn.13710\" target=\"_blank\" rel=\"noopener\">Link<\/a>. <\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A recent study by researchers at Fukui University in Japan has identified a possible link between certain fatty acids in [&hellip;]<\/p>\n","protected":false},"author":2284,"featured_media":584486,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"two_page_speed":[],"_wpcom_ai_launchpad_first_post":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[107085],"tags":[108464],"class_list":["post-596656","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-estudio-en"],"jetpack_sharing_enabled":true,"jetpack_likes_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/pdR79Q-2vdu","jetpack-related-posts":[{"id":584475,"url":"https:\/\/cerebrodigital.net\/estudio-sugiere-nueva-clave-biologica-para-tea\/","url_meta":{"origin":596656,"position":0},"title":"Una nueva clave biol\u00f3gica del autismo: Un estudio japon\u00e9s sugiere una posible causa prenatal","author":"Denis Carrillo","date":"June 9, 2025","format":false,"excerpt":"Un reciente estudio llevado a cabo por investigadores de la Universidad de Fukui, en Jap\u00f3n, ha identificado un posible v\u00ednculo entre ciertos \u00e1cidos grasos en la sangre del cord\u00f3n umbilical y el desarrollo del trastorno del espectro autista (TEA). Este hallazgo podr\u00eda significar un avance decisivo en el diagn\u00f3stico temprano,\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/category\/ciencia\/"},"img":{"alt_text":"Estudio","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":597137,"url":"https:\/\/cerebrodigital.net\/en\/neanderthal-legacy-in-our-brain-a-possible-connection-with-autism\/","url_meta":{"origin":596656,"position":1},"title":"Neanderthal Legacy in Our Brain: A Possible Connection with Autism","author":"Erick Sumoza","date":"July 11, 2025","format":false,"excerpt":"Neanderthal\u00a0DNA\u00a0still lives in us. A recent study published in\u00a0Molecular Psychiatry\u00a0suggests that certain fragments inherited from these\u00a0ancient hominids\u00a0could influence traits of autism spectrum disorder (ASD). Far from being an irrelevant vestige, this genetic legacy raises new questions about human evolution and the richness of neurodiversity. Neanderthals and Modern Humans: A Shared\u2026","rel":"","context":"In &quot;Educaci\u00f3n&quot;","block_context":{"text":"Educaci\u00f3n","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/noticias-educacion-en\/"},"img":{"alt_text":"Neardental","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/07\/image-17.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/07\/image-17.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/07\/image-17.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/07\/image-17.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/07\/image-17.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":595471,"url":"https:\/\/cerebrodigital.net\/en\/taiwan-fight-against-baldness\/","url_meta":{"origin":596656,"position":2},"title":"Taiwan joins the fight against baldness with a new treatment that promises to create \u201cnew hair\u201d","author":"Erick Sumoza","date":"December 4, 2025","format":false,"excerpt":"Baldness has long been seen as an irreversible process once the follicle \u201cdies.\u201d However, a monumental breakthrough in cell biology is challenging this belief. Researchers at National Taiwan University (NTU) have identified a natural mechanism that acts as a \u201cmaster switch\u201d to reactivate hair growth. This discovery, focused on dormant\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"Taiw\u00e1n se une a la lucha contra la calvicie con un nuevo tratamiento que promete crear \"cabello nuevo\"","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/12\/image-9.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/12\/image-9.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/12\/image-9.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/12\/image-9.jpeg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/12\/image-9.jpeg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":596536,"url":"https:\/\/cerebrodigital.net\/en\/endodontics-and-metabolism-what-science-reveals-about-the-connection-between-the-mouth-and-the-body\/","url_meta":{"origin":596656,"position":3},"title":"Endodontics and Metabolism: What Science Reveals About the Connection Between the Mouth and the Body","author":"Erick Sumoza","date":"February 28, 2026","format":false,"excerpt":"Oral health influences much more than a smile. A recent study published in Journal of Translational Medicine found that treating endodontic infections could improve metabolic parameters such as glucose and lipids. These findings reinforce the relationship between oral inflammation and overall systemic health. Scientific Evidence: Results of the Longitudinal Study\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"Endodoncia y metabolismo: lo que revela la ciencia sobre la conexi\u00f3n entre boca y el cuerpo","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-134.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-134.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-134.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-134.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-134.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":595940,"url":"https:\/\/cerebrodigital.net\/en\/polylaminin-breakthrough-spinal-cord-injury\/","url_meta":{"origin":596656,"position":4},"title":"Polylaminin: the Brazilian breakthrough that could revolutionize spinal cord injury treatment","author":"Erick Sumoza","date":"February 13, 2026","format":false,"excerpt":"For decades, spinal cord injury has been one of the greatest challenges of modern medicine. Now, research led by biologist Tatiana Coelho Sampaio from the Federal University of Rio de Janeiro (UFRJ) introduces a possible therapeutic alternative based on polylaminin, an experimental protein that has shown promising preliminary results in\u2026","rel":"","context":"In \"Science\"","block_context":{"text":"Science","link":"https:\/\/cerebrodigital.net\/en\/tag\/science\/"},"img":{"alt_text":"Polilaminina: el avance brasile\u00f1o que podr\u00eda revolucionar el tratamiento de la lesi\u00f3n medular","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-76.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-76.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-76.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-76.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-76.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":596077,"url":"https:\/\/cerebrodigital.net\/en\/erythritol-study-reveals-about-brain-barrier\/","url_meta":{"origin":596656,"position":5},"title":"Erythritol under scientific scrutiny: what a study reveals about the brain barrier","author":"Erick Sumoza","date":"February 18, 2026","format":false,"excerpt":"Erythritol is a popular sweetener in sugar-free products, valued for its low metabolic impact. However, recent research has analyzed its effects on the cells that protect the brain. A study in the Journal of Applied Physiology provides evidence on how it could affect cerebral vascular function. What erythritol is and\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"El eritritol bajo la lupa cient\u00edfica: lo que revela un estudio sobre la barrera cerebral","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-98.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-98.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-98.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-98.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2026\/02\/image-98.png?resize=1050%2C600&ssl=1 3x"},"classes":[]}],"amp_enabled":true,"jetpack_featured_media_url":"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/image-24.png","_links":{"self":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/596656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/users\/2284"}],"replies":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/comments?post=596656"}],"version-history":[{"count":4,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/596656\/revisions"}],"predecessor-version":[{"id":596660,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/596656\/revisions\/596660"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/media\/584486"}],"wp:attachment":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/media?parent=596656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/categories?post=596656"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/tags?post=596656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}