{"id":533493,"date":"2023-03-09T23:00:29","date_gmt":"2023-03-10T05:00:29","guid":{"rendered":"https:\/\/cerebrodigital.net\/scientists-complete-the-first-map-of-the-insect-brain\/"},"modified":"2023-03-22T16:33:51","modified_gmt":"2023-03-22T22:33:51","slug":"scientists-complete-the-first-map-of-the-insect-brain","status":"publish","type":"post","link":"https:\/\/cerebrodigital.net\/en\/scientists-complete-the-first-map-of-the-insect-brain\/","title":{"rendered":"Scientists complete the first map of the insect brain"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Researchers have completed the <a href=\"https:\/\/hub.jhu.edu\/2023\/03\/09\/scientists-complete-first-map-of-an-insect-brain\/\" target=\"_blank\" rel=\"noopener\">most advanced brain map<\/a> to date, that of an insect, a landmark achievement in neuroscience that brings scientists closer to truly understanding the mechanism of thought.<\/p>\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline-1024x576.jpg\" alt=\"-\" class=\"wp-image-524847\" width=\"512\" height=\"288\" title=\"\" srcset=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline-1024x576.jpg 1024w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline-300x169.jpg 300w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline-768x432.jpg 768w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline-150x84.jpg 150w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/recontruccion_cerebro_nueronas_animal_kjvg-bspline.jpg 1200w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.add9330\" target=\"_blank\" rel=\"noopener\">international team<\/a> led by Johns Hopkins University and the University of Cambridge produced an impressively detailed diagram that traces every neural connection in the brain of a fruit fly larva, an archetypal scientific model with brains comparable to humans.<\/p>\n\n<p class=\"wp-block-paragraph\">The work, which is likely to underpin future brain research and inspire new machine learning architectures.<\/p>\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Complete Set of Neurons in an Insect Brain\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/NXr0ZdoYgRw?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n<p class=\"wp-block-paragraph\">Lead author Joshua T. Vogelstein, a biomedical engineer at Johns Hopkins who specializes in data-driven projects, including connectomics, the study of nervous system connections said:<\/p>\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">&#8220;If we want to understand who we are and how we think, part of that is understanding the mechanism of thought.&#8221;<\/p>\n<cite>&#8220;And the key to that is knowing how neurons are wired together.&#8221;<\/cite><\/blockquote>\n\n<p class=\"wp-block-paragraph\">The first attempt to map a brain: a 14-year study of the roundworm initiated in the 1970s resulted in a partial map and a Nobel Prize. Since then, partial connectomes have been mapped in many systems, including flies, mice and even humans, but these reconstructions generally represent only a small fraction of the whole brain. Complete connectomes have only been generated for several small species with a few hundred to a few thousand neurons in their bodies: a roundworm, a sea squirt larva, and a marine annelid worm larva.<\/p>\n\n<p class=\"wp-block-paragraph\">This team&#8217;s connectome of a fruit fly hatchling, the larva of Drosophila melanogaster , is the most complete and extensive map of a whole insect brain ever completed. It includes 3,016 neurons and each connection between them: 548,000.<\/p>\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" width=\"820\" height=\"397\" src=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/cerebro-delarva-de-mosca-kjhgv.jpg\" alt=\"-\" class=\"wp-image-524849\" title=\"\" srcset=\"https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/cerebro-delarva-de-mosca-kjhgv.jpg 820w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/cerebro-delarva-de-mosca-kjhgv-300x145.jpg 300w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/cerebro-delarva-de-mosca-kjhgv-768x372.jpg 768w, https:\/\/cerebrodigital.net\/wp-content\/uploads\/2023\/03\/cerebro-delarva-de-mosca-kjhgv-150x73.jpg 150w\" sizes=\"(max-width: 820px) 100vw, 820px\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\">Vogelstein said:<\/p>\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">&#8220;It&#8217;s been 50 years and this is the first brain connectome. It&#8217;s a flag in the sand that we can do this.&#8221;<\/p>\n<cite>&#8220;Everything has been working until this.&#8221;<\/cite><\/blockquote>\n\n<p class=\"wp-block-paragraph\">Mapping whole brains is difficult and time-consuming, even with the best modern technology. Obtaining a complete cellular-level image of a brain requires slicing the brain into hundreds or thousands of individual tissue samples, all of which have to be captured with electron microscopes before the painstaking process of reconstructing all those pieces, neuron by neuron, into a complete, accurate portrait image of a brain.<\/p>\n\n<p class=\"wp-block-paragraph\">It took more than a decade to do that with baby fruit flies. The brain of a mouse is estimated to be one million times larger than that of a baby fruit fly, which means that the possibility of mapping anything resembling a human brain is not likely in the near future, perhaps not even in our lifetimes.<\/p>\n\n<p class=\"wp-block-paragraph\">The team deliberately chose fruit fly larvae because, for an insect, the species shares much of its fundamental biology with humans, including a comparable genetic base. It also has rich learning and decision-making behaviors, making it a useful model organism in neuroscience. And for practical purposes, their brains can be imaged relatively compactly and their circuits can be reconstructed in a reasonable time frame.<\/p>\n\n<p class=\"wp-block-paragraph\">Even so, the work took the University of Cambridge and Johns Hopkins 12 years. The imaging alone took about one day per neuron.<\/p>\n\n<p class=\"wp-block-paragraph\">The Cambridge researchers created the high-resolution images of the brain and studied them manually to find individual neurons, rigorously tracing each one and linking their synaptic connections.<\/p>\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Complete Brain Map of Fruit Fly Larva\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/p09VcqqFpGc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n<p class=\"wp-block-paragraph\">Cambridge delivered the data to Johns Hopkins, where the team spent more than three years using the original code they created to analyze brain connectivity. The Johns Hopkins team developed techniques to find clusters of neurons based on shared connectivity patterns and then analyzed how the information might propagate through the brain.<\/p>\n\n<p class=\"wp-block-paragraph\">In the end, the entire team recorded every neuron and every connection, and classified each neuron according to the role it plays in the brain. They found that the most active circuits in the brain were those going to and from neurons in the learning center.<\/p>\n\n<p class=\"wp-block-paragraph\">The methods developed by Johns Hopkins are applicable to any brain wiring project, and their code is available to anyone trying to map an even larger animal brain, Vogelstein said, adding that, despite the challenges, scientists are expected to tackle the mouse, possibly within the next decade. Other teams are already working on a map of the adult fruit fly brain.<\/p>\n\n<p class=\"wp-block-paragraph\">Co-author Benjamin Pedigo, a PhD candidate in biomedical engineering at Johns Hopkins, hopes the team&#8217;s code can help reveal important comparisons between connections in the adult and larval brain. As connectomes are generated for more larvae and other related species, Pedigo hopes that his analysis techniques can lead to a better understanding of variations in brain wiring.<\/p>\n\n<p class=\"wp-block-paragraph\">The fruit fly larvae work showed circuit characteristics that were strikingly reminiscent of prominent and powerful machine learning architectures. The team expects the ongoing study to reveal even more computational principles and potentially inspire new artificial intelligence systems.<\/p>\n\n<p class=\"wp-block-paragraph\">Vogelstein said:<\/p>\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">&#8220;What we learned about the code of fruit flies will have implications for the code of humans.&#8221;<\/p>\n<cite>&#8220;That&#8217;s what we want to understand: how to write a program that leads to a human brain network.&#8221;<\/cite><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have completed the most advanced brain map to date, that of an insect, a landmark achievement in neuroscience that 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revolutionary map of the human brain: the intersection between neuroscience and engineering","author":"Erick Sumoza","date":"March 5, 2025","format":false,"excerpt":"For over a decade, an engineer specialized in space shuttle guidance systems and software development has compiled a detailed\u00a0brain map\u00a0without external funding from companies, religions, or scientific organizations. This work, based on the analysis of thousands of neuroscientific studies, reveals the complex organization of the human brain and its similarity\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"Un revolucionario mapa del cerebro humano: la intersecci\u00f3n entre neurociencia e ingenier\u00eda","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/03\/portada-6.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/03\/portada-6.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/03\/portada-6.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/03\/portada-6.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/03\/portada-6.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":538403,"url":"https:\/\/cerebrodigital.net\/en\/this-is-the-most-relaxing-song-in-the-world-according-to-science-eacr\/","url_meta":{"origin":533493,"position":1},"title":"This is the most relaxing song in the world, according to science","author":"Andrey Robles","date":"May 25, 2023","format":false,"excerpt":"New Zealand alt-pop artist Benee has combined her favourite comfort food with expertise from neuroscientists to design a song, Bagels, that reduced anxiety more effectively than the track previously known as the most relaxing song in the world. Scientists from Auckland University of Technology played Bagels to 30 young people\u2026","rel":"","context":"In &quot;Mental health&quot;","block_context":{"text":"Mental health","link":"https:\/\/cerebrodigital.net\/en\/category\/health\/mental-health\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/05\/la_cancion_mas_relajante_jkhgv-bicubic.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/05\/la_cancion_mas_relajante_jkhgv-bicubic.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/05\/la_cancion_mas_relajante_jkhgv-bicubic.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/05\/la_cancion_mas_relajante_jkhgv-bicubic.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/05\/la_cancion_mas_relajante_jkhgv-bicubic.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":547424,"url":"https:\/\/cerebrodigital.net\/en\/phineas-gage-survive-destroyed-frotal-lobe\/","url_meta":{"origin":533493,"position":2},"title":"Phineas Gage: How did he survive a steel rod that pierced and destroyed his frontal lobe?","author":"Erick Sumoza","date":"October 28, 2023","format":false,"excerpt":"If someone manages to survive a more than one-meter-long metal rod passing through their skull, it's no wonder they are still being talked about 150 years later. That was the case with Phineas Gage. In 1848, 25-year-old Gage suffered an accident where an explosion embedded a rod into his head.\u2026","rel":"","context":"In &quot;History&quot;","block_context":{"text":"History","link":"https:\/\/cerebrodigital.net\/en\/category\/history\/"},"img":{"alt_text":"Phineas Gage: How did he survive a steel rod that pierced and destroyed his frontal lobe?","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/10\/phineas-gage-how-did-he-survive-a-steel-rod-that-pierced-and-destroyed-his-frontal-lobe-cover-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/10\/phineas-gage-how-did-he-survive-a-steel-rod-that-pierced-and-destroyed-his-frontal-lobe-cover-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/10\/phineas-gage-how-did-he-survive-a-steel-rod-that-pierced-and-destroyed-his-frontal-lobe-cover-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/10\/phineas-gage-how-did-he-survive-a-steel-rod-that-pierced-and-destroyed-his-frontal-lobe-cover-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/10\/phineas-gage-how-did-he-survive-a-steel-rod-that-pierced-and-destroyed-his-frontal-lobe-cover-1.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":585526,"url":"https:\/\/cerebrodigital.net\/en\/dreams-recorded-played-device\/","url_meta":{"origin":533493,"position":3},"title":"Dreams Can Now Be Recorded and Played Back Thanks to a Device Created by Japanese Scientists","author":"Erick Sumoza","date":"June 26, 2025","format":false,"excerpt":"A group of researchers in Japan has achieved what once seemed the stuff of science fiction: recording and reproducing dreams. These experts have developed a technology capable of capturing and projecting what we dream in real time\u2014a groundbreaking innovation in the exploration of the human mind. A Window into the\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"Los sue\u00f1os ahora pueden ser grabados y reproducidos gracias a un dispositivo creado por cient\u00edficos japoneses","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-47.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-47.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-47.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-47.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-47.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":584852,"url":"https:\/\/cerebrodigital.net\/en\/chinas-brain-implants-paralyzed-patients\/","url_meta":{"origin":533493,"position":4},"title":"China&#8217;s Brain Implants Enable Paralyzed Patients to Walk Again","author":"Erick Sumoza","date":"June 16, 2025","format":false,"excerpt":"A clinical trial conducted in Shanghai has pushed the boundaries of neurological medicine with brain implants. Four patients paralyzed due to spinal cord injuries regained leg movement following an innovative surgery that reconfigures the nervous system without relying on robotic prosthetics. Chinese Brain Implants Outperform Neuralink\u2019s Surgery to place the\u2026","rel":"","context":"In &quot;Ciencia&quot;","block_context":{"text":"Ciencia","link":"https:\/\/cerebrodigital.net\/en\/category\/news-en\/ciencia-noticias-en\/"},"img":{"alt_text":"Los implantes cerebrales de China hacen que pacientes paralizados vuelvan a caminar","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-30.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-30.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-30.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-30.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2025\/06\/portada-30.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":535095,"url":"https:\/\/cerebrodigital.net\/en\/oldest-preserved-brain-in-the-world-found-in-a-319-million-year-old-fish-fossil-eacr\/","url_meta":{"origin":533493,"position":5},"title":"The world&#8217;s oldest preserved brain found in a 319-million-year-old fish fossil","author":"Andrey Robles","date":"April 1, 2023","format":false,"excerpt":"In general, fish are not known to be intelligent creatures with tremendous brain power. Many believe that Goldfish, in particular, have memory lapses of three seconds, but that is not true. The brain of another fish recently grabbed the spotlight for a different reason. A 319-million-year-old fish fossil at Manchester\u2026","rel":"","context":"In &quot;Exploring the world&quot;","block_context":{"text":"Exploring the world","link":"https:\/\/cerebrodigital.net\/en\/category\/lifestyle\/exploring-the-world\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/04\/cerebro_pez_antiguo_kjhb-triangle.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/04\/cerebro_pez_antiguo_kjhb-triangle.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/04\/cerebro_pez_antiguo_kjhb-triangle.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/04\/cerebro_pez_antiguo_kjhb-triangle.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/cerebrodigital.net\/wp-content\/uploads\/2023\/04\/cerebro_pez_antiguo_kjhb-triangle.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]}],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/533493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/comments?post=533493"}],"version-history":[{"count":1,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/533493\/revisions"}],"predecessor-version":[{"id":533502,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/posts\/533493\/revisions\/533502"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/media\/533307"}],"wp:attachment":[{"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/media?parent=533493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/categories?post=533493"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cerebrodigital.net\/en\/wp-json\/wp\/v2\/tags?post=533493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}